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Degradants cefadroxil

Figure 6.30 The mass chromatograms (EIC profiles) of selected degradants at the m/z values corresponding to their [M+H]+ ions in a base-degraded cefadroxil monohydrate sample. (Reprinted with permission from Rourick et al., 1996. Copyright 1996 Elsevier.)... Figure 6.30 The mass chromatograms (EIC profiles) of selected degradants at the m/z values corresponding to their [M+H]+ ions in a base-degraded cefadroxil monohydrate sample. (Reprinted with permission from Rourick et al., 1996. Copyright 1996 Elsevier.)...
A. Tsuji, E. Nakashima, Y. Deguchi, K. Nishide, T. Shimizu, S. Horiuchi, K. Ishikawa, T. Yamana, Degradation Kinetics and Mechanism of Aminocephalosporins in Aqueous Solution Cefadroxil , J. Pharm. Sci. 1981, 70, 1120-1128. [Pg.246]

TABLE 6.15 Library of cefadroxil degradants and impurities obtained from predictive profiles obtained by exposing the drug to the various development conditions shown in Table 6.14... [Pg.143]

Tsuji A, Nakashima E, Deguchi Y, et al. Degradation kinetics and mechanism of amino-cephalosporins in aqueous solution Cefadroxil. J Pharm Sci 1981 70 1120-8. [Pg.458]

FiguK 3.6 Molecular structures of the native and ring open hydrolysed degradent of cefadroxil. Arrows highlight the hydrogen bonded water that is present in the crystal. The hydrolysis proceeds readily in aqueous solution but not in the crystalline hydrate... [Pg.82]

Lorenz, LJ. Bashore, F.N. Olsen, B.A. Determination of process-related impurities and d adation products in cefaclor by hi -performance liquid chromatography. J.Chromatogr.ScL, 1992,30,211— 216 determination, [simultaneous impurities, degradation products bulk gradient coliunn temp 25] Nahata, M.C. Jackson, D.S. Liquid chromatographic method for the determination of cefadroxil in its suspension and in serum. J.Liq.Chromatogr., 1990,13,1651-1656 [simultaneous cefadroxil sui n-sions cefaclor is IS]... [Pg.264]

See other pages where Degradants cefadroxil is mentioned: [Pg.533]    [Pg.653]    [Pg.680]    [Pg.142]    [Pg.143]    [Pg.144]    [Pg.308]    [Pg.3430]    [Pg.264]    [Pg.116]    [Pg.137]   
See also in sourсe #XX -- [ Pg.140 , Pg.141 , Pg.142 , Pg.143 , Pg.144 ]



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Cefadroxil

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