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Definition gene-specific effect

Comparative structural analysis of sodium channel genes has permitted the development of testable hypotheses concerning the neurotoxin recognition properties of the sodium channel protein. However, specific elements of the deduced structure have not yet been definitively correlated with the molecular recognition of sodium channel-directed neurotoxins by discrete binding domains. It is, thus, not possible at the present time to know which pharmacological properties are determined by the sodium channel protein per se and which are determined by interactions between it and crucial features of its membrane environment. Clearly, it will be necessary to analyze the effects of specific modifications of sodium channel structure in a defined membrane environment in order to address these and other questions relating to sodium channel function. [Pg.207]

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See also in sourсe #XX -- [ Pg.375 ]



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Effective definition

Effectiveness definition

Genes definition

Specific definition

Specific effects

Specification effective

Specifications definition

Specificity, definition

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