Databases toxicogenomic

Use of Reference Databases to Interpret Toxicogenomic Results and Predict Potential Human Toxicity... 

Mattingly, C.J., Rosenstein, M.C., Davis, A.P., Colby, G.T., ForrestJJr., J.N. and Boyer, J.L. (2006) The Comparative Toxicogenomics Database a cross-species resource for building chemical-gene interaction networks. Toxicol. Sci., 92 (2), 587-595. 

Ganter B, Zidek N, Hewitt PR, et al. Pathway analysis tools and toxicogenomics reference databases for risk, Pharmacogenomics. 2008 9(l) 35-54. 

Public databases allow the scientihc community to publish, share, and compare the data obtained from toxicology and toxicogenomics experiments (see Chapter 6). They are a resource for data mining, and for the discovery of novel genes/proteins through their coexpression with known molecules. They also help to identify and minimize the use of experimental practices that introduce undesirable variability into toxicogenomics datasets. 

Mattes WB, Pettit SD, Sansone SA, Bushel PR, Waters MD. Database development in toxicogenomics Issues and efforts. Environ Health Perspect 2004 112(4) 495-505. 

Mattingly CJ, Colby GT, Rosenstein MC, Forrest JN, Jr, Boyer JL. Promoting comparative molecular studies in environmental health research An overview of the comparative toxicogenomics database (CTD). Pharmacogenomics J2004 4(1) 5-8. 

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