Danshen Digoxin

Chow L, Johnson M, Wells A, Dasgupta A. Effect of traditional Chinese medicines chan su, lu-shen-wan, danshen and Asian ginseng on serum digoxin measurement by Tina-Quant (Roche) and Synchron LX system (Beckman) digoxin immunoassays. J Clin Lab Anal 2003 17 22-27. 

Another report describes a man taking warfarin, digoxin, captopril and furosemide with an INR of about 3, who developed chest pain and breathlessness about 2 weeks after starting to take Danshen. He was found to have a massive pleural effusion, which was later drained of blood, and an USTR of more than 8.4. He was later discharged on his usual dose of warfarin with an INR stable at 3, in the absence of the Danshen ... 

Dasgiqita A, Kang E, Olsen M, Actor JK, Datta P. New enzyme-linked chemiluminescent immunosorbent digoxin assay is free from interference of Chinese m edicine DanShen. TherDrug MordtC2006) 28, 775-8. 

Dasgupta, A., J.K. Actor, M. Olsen, A. Wells, and P. Datta. 2002. In vivo digoxin-like immunoreactivity in mice and interference of Chinese medicine danshen in semm digoxin measurement Elimination of interference by using a chemiluminescent assay. Clin. Chim. Acta 317(l-2) 231-234. 

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