Danazol drug interactions

Kramer G, Theisohn M, von Unruh GE, Eichelbaum M. Carbamazepine-danazol drug interaction its mechanism examined by a stable isotope technique. TherDrugMomt 9Z6) 8, 387-92. 

A potential drug interaction between simvastatin and danazol, causing rhabdomyolysis and acute renal insufficiency, has been reported (43). Rhabdomyolysis can occur with all statins when they are used alone and particularly when they are combined with other drugs that are themselves myotoxic or that increase the concentration of the statin. Statins are particularly susceptible to the latter effect because of their metabolism by the CYP450 system and their low oral systemic availability. 

Andreou ER. Potential drug interaction between simvastatin and danazol causing rhabdomyolysis. Can J Clin Pharmacol 2003 10 172-4. 

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