Dalbergions

Cases of dermatitis have been described since 1934 and have been observed in clarinet makers and in knife-handle turners (Meister 1934 Woods and Calnan 1976 Hausen et al. 1984). The responsible allergens are (S) -4-methoxydalbergion, (S) -4 -hydroxy-4-methoxy-dalbergion and (S)-3 -hydroxy-4,4 -dimethoxydalber-gione (Schulz et al. 1979). 

S)-4,4 -Dimethoxydal bergion (R = OCH3) (S)-4 -Hydroxy-4-methox-dalbergion (R = OH)... 

Dalbergia latifolia East Indian rosewood, Bombay blackwood, sissoo Dalbergione 10% Sawdust in pet. India. Mathematical instruments, furniture, and veneers... 

S-4 -Hydroxy 4-methoxy dalbergione is one of the allergens of Dalbergia nigrUy Dalbergia retusa and Dalbergia melanoxylon. 

R)-4-Methoxy dalbergione is the main allergen of Dalbergia nigra and Dalhergia latifolia Roxb. (East Indian rosewood, palissandre). Occupational sensitization occurs in timberworkers. 

Dalbergione, 4-methoxy- and 4, 4 -dimethoxy-, Y4 Dammarenediols, T51 Dammarenolic acid, T51 Daphmacrine, K26 Daphnetoxin, T39 Daphniphyllum alkaloids, K26 Daphylloside, T15 Daucol, T25 Daucone, T25 Daunomycin, Y28 Daunomycinone trimethyl ether, Y28... 

Closely related both structurally and biogenetically to the flavonoids are two groups of natural products—the isoflavonoids and neoflavonoids. In contrast to the flavonoids however, these groups are of a more limited taxonomic distribution in higher plants and are found primarily in the Leguminosae. Isoflavonoids have in common the 1,2-diphenyl propane skeleton (11) and include many classes of natural product such as the isoflavones, isoflava-nones, rotenoids, pterocarpans and coumestans. The term neo-flavonoid was introduced by Ollis and his associates to cover the third group of compounds which possess the 1,1-diarylpropane skeleton (12) and includes such compounds as the 4-phenyl-coumarins and the various dalbergiones. 

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