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Cytotoxic T-lymphocyte associated antigen

Abrams, J.R. et al., Blockade of T lymphocyte costimulation with Cytotoxic T Lymphocyte-associated Antigen 4-Immunoglobulin (CTL A4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells, J. Exp. Med., 192, 691, 2000. [Pg.139]

Read S, Malmstrom V, Powrie F Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25 -I- CD4 -I- regulatory cells that control intestinal inflammation. J Exp Med 2000 192 295-302. [Pg.175]

Sutmuller RP, van Duivenvoorde LM, van Elsas A, Schumacher TN, Wildenberg ME, Allison JP, et al Synergism of cytotoxic T lymphocyte-associated antigen-4 blockade and depletion of CD25 + regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. [Pg.176]

Maker AZ et al Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2 A phase I/II study. Ann Surg Oncol 2005 12 1004. [Pg.1208]

Phan GQ et al Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A 2003 100 8372. [PMID 12826605]... [Pg.1208]

Consists of the extracellular domain of human cytotoxic T lymphocyte associated antigen 4 (CTLA-4) linked to the modified Fc (hinge,... [Pg.444]

Soluble fusion protein that consists of the extracellular domain of human cytotoxic T lymphocyte associated antigen 4 (CTLA-4) linked to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin IgG binds to T lymphocyte antigens CD80 and CD86 thus blocking interaction with CD 28... [Pg.952]

Zlru J, Zou LP, Zlru SW, Mix E, Slii ED, Warrg HB, Volkmarrn I, Winblad B, Schallirrg M, Ljunggren HG (2001a) Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade enhances incidence and severity of experimental autoimmune neuritis in resistant mice. J Neuroimmunol 115 111—117. [Pg.282]

Darlington P, Baroja M, Chau T, Siu E, Ling V, Carreno B, Madrenas J Surface cytotoxic T lymphocyte-associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition ofT cell activation. J Exp Med 2002 195 1-12. [Pg.178]

Parks CG, Cooper GS, Hudson LL, Dooley MA, Treadwell EL, St Clair EW, Gilkeson GS, Pandey JP (2005) Association of Epstein-Barr virus and systemic lupus erythematosus effect modification by race, age and cytotoxic T lymphocyte-associated antigen 4 genotype. Arthritis Rheum, 52 1148-1159. [Pg.300]

CTLA cytotoxic T lymphocyte associated antigen receptor... [Pg.500]

See other pages where Cytotoxic T-lymphocyte associated antigen is mentioned: [Pg.176]    [Pg.129]    [Pg.140]    [Pg.510]    [Pg.175]    [Pg.17]    [Pg.1199]    [Pg.102]    [Pg.18]    [Pg.448]    [Pg.615]    [Pg.5]    [Pg.693]    [Pg.156]    [Pg.192]    [Pg.239]    [Pg.240]    [Pg.311]    [Pg.451]    [Pg.136]    [Pg.109]   


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