Cytoskeleton dynamics

In order to anticipate possible modes of regulation of cytoskeleton dynamics in vivo, it is necessary (a) to identify the kinetic intermediates involved in the polymerization process and to characterize their structural and functional properties and (b) to define the essential elementary steps in the hydrolysis process. 

Stewart, M., and Roberts, T. M. (2005). Cytoskeleton dynamics powers nematode sperm motility. Adv. Protein Chem. 71, 383-399. 

CYTOSKELETON DYNAMICS POWERS NEMATODE SPERM MOTILITY... 

Imaging Actin Cytoskeleton Dynamics in Dictyostelium Chemotaxis... 

G., and MiiUer-Taubenberger, A. (2004) A brilliant monomeric red fluorescent protein to visualize cytoskeleton dynamics in Dictyostelium. FEBS Lett. 577, 227-232... 

Sechi, A. S. and Wehland, J. (2004) Ena/ VASP proteins multifunctional regulators of actin cytoskeleton dynamics. Front. Biosci. 9, 1294-1310. 

Study of in vivo cytoskeleton dynamics. 38 Labels of phalloidin and phallacidin are used for selectively labeling F-actin. 

Sheetz, M.P., Sable, J.E., Dobereiner, H. Continuous membrane-cytoskeleton adhesion requires continuous accommodation to lipid and cytoskeleton dynamics. Ann. Rev. Biophys. Biomol. Struct 35,417-434 (2006)... 

Dhonukshe, P., Grigoriev, I., Fischer, R. et al. (2008). Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes. Proceedings of the National Academy of Sciences, 105,4489-4494. 

Movement is an essential function in cellular system. Chemical interactions of proteins are microscopic movements of proteins, namely, diffusion, transport and the collision among the proteins. Vesicles containing proteins move to specific sites within cell for their destined functions. Chromosomes move to separate from each other during cell division. Cytoskeleton dynamically forms bundles and networks to afford routes for the intracellular trafficking and to control the physical architecture of the cell. Cells themselves move by migration. Within multicellular structure, cell movement drives the morphogenesis and preserves the homeostasis. Measurement of these various movements provides quantitative information that is inevitable for understanding the cellular system. 

Edwards K.A., Demsky M., Montaque R.A, Weymouth N., and Kiehart D.R 1997. GFP-moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila. Dev. Biol. 191 103-117. 

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