Cytoplasm, DNA synthesis

While the synthesis of mitochondrial DNA observed in cultured animal cells in the G2 phase may result from the method used to synchronize the cells (Koch and Stokstad, 1967 Watson and Kidson, 1970), it remains that the initiation of DNA synthesis in various cell organelles can take place at different times during the cell division cycle. Differences in the patterns of nuclear and cytoplasmic DNA synthesis found in various eukaryotes may mean that no rule exists to describe the time in the cell cycle that ach occurs. Important here is the conclusion that organelle-specific mechanisms must exist to regulate the initiation of DNA synthesis at these different times in the cell cycle. 

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