Cytidine complexes

C7H603 C9H13N305 Salicylic acid-cytidine complex (SALCYS)284... 

C7H603 CaH NaOB Salicylic acid-cytidine complex SALCYS 43 357... 

Borah B, Wood JL (1976) The cytidinium-cytidine complex infrared and Raman spectroscopic studies. J Mol Struct 30 13-30... 

Finally, De Munno et al. reported the one-pot synthesis of a stable polynuclear copper(n)-cytidine complex, entitled as the nucleoside-wheel . Surprisingly, despite the positive charges from eight copper(II) centers the complex is able to act as a host for [Cu(H20)6] cations. These unique complexes provide new opportunities for specific molecular recognition in the broad field of host-guest chemistry [67]. 

Dependence of tt complex binding constants upon nucleoside ionization potentials for ( ) uridine, ( ) thymidine, (A) cytidine, (o) adenosine, (O) guanosine, and (A) N,N,-dimethyladenosine. Panel A shows association constants for the binding of nucleosides to riboflavin. Panel B shows association constants for the self association of nucleosides. (Reproduced from Ref. 82. Copyright 1981, American Chemical Society.)... 

Table XIX contains stability constants for complexes of Ca2+ and of several other M2+ ions with a selection of phosphonate and nucleotide ligands (681,687-695). There is considerably more published information, especially on ATP (and, to a lesser extent, ADP and AMP) complexes at various pHs, ionic strengths, and temperatures (229,696,697), and on phosphonates (688) and bisphosphonates (688,698). The metal-ion binding properties of cytidine have been considered in detail in relation to stability constant determinations for its Ca2+ complex and complexes of seven other M2+ cations (232), and for ternary M21 -cytidine-amino acid and -oxalate complexes (699). Stability constant data for Ca2+ complexes of the nucleosides cytidine and uridine, the nucleoside bases adenine, cytosine, uracil, and thymine, and the 5 -monophosphates of adenosine, cytidine, thymidine, and uridine, have been listed along with values for analogous complexes of a wide range of other metal ions (700). Unfortunately comparisons are sometimes precluded by significant differences in experimental conditions.

LogK values for analogous complexes derived from cytidine, thymidine, or uridine are... 

Example 5 Hayakawa and Noyori group in their studies on new activators for phosphoroamidite coupling reactions have applied the most effective member of the group of acid/azole complexes AT-(phenyl)imidazolium tri-flate (N-PhIMT) in the efficient synthesis of biologically important compounds [20j]. A noteworthy example is synthesis of cytidine-5 -monophos-pho-AT-acetylneuraminic acid. This compound is a source of sialic acid in the sialyltransferase-catalysed biosynthesis of sialyl oligosaccharides [25]. 

CYSTATHIONINE /3-LYASE CYTIDINE DEAMINASE CYTIDYLATE KINASE Cytochrome be, complex,... 

The presence of such a mechanism was prohed hy varying the sweep rate as illustrated in Fig. 4. Caution must he exercised in drawing conclusions from such a study because, with hahde ions (and with some other unidentate species), bridging by the halide between the copper ion and the electrode surface may accelerate the rate of electron transfer and lead to erroneous conclusions. This type of mechanism has also been proposed by Palaniandavar and coworkers [121] for the Cu(II/I) complex with deprotonated salicylideneglycine in the presence of cytosine or cytidine in which the latter species tends to be coordinated only to the oxidized complex. 

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