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CYP2D6 genotype

Kubo, M. et al. (2005). Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic Aripriprazole. Drug Metab. Pharmacokinet.,... [Pg.57]

Shimoda, K. et al. (2002). The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. /. Clin. Psychopharmacol., 22, 371-8. [Pg.60]

Yue, Q.Y. et al. (1998). Pharmacokinetics of nortriptyline and its 10-hydroxy metabolite in Chinese subjects of different CYP2D6 genotypes. Clin. Pharmacol. Ther., 64, 384-90. [Pg.61]

Two additional pharmacogenetic studies utilized the Los Angeles Mexican American study sample previously cited (Mendoza etal, 2001). First, Luo etal. (2005) extended the CYP2D6 genotyping analysis further to include 6, 7, 8,... [Pg.103]

Cholerton S et al. CYP2D6 genotypes in cigarette smokers and non-tobacco users. Pharmacogenetics 1996 6(3) 261— 263. [Pg.458]

Wennerholm A, Johansson I, Massele AY, Jande M, Alm C, Aden-Abdi Y et al. Decreased capacity for debrisoquine metabolism among black Tanzanians analyses of the CYP2D6 genotype and phenotype. Pharmacogenetics 1999 9 707-714. [Pg.510]

C., Warzok, R., Engel, G. Weitschies, W., Cascorbi, I., Kroemer, H.K. and Siegmund, W. (2004) CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects. Clinical Pharmacology and Therapeutics, 75, 213-222. [Pg.365]

Jin, Y., Desta, Z., Stearns, V., et al. (2005) CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J. Natl. Cancer Inst. 97, 30-39. [Pg.72]

In the Spanish population, for whom the mixture of ancestral cultures has occurred for centuries, the distribution of the CYP2D6 genotypes differentiates four major categories of CTP2D6-related metabolizer types (1) EMs ( 7/7, IPIO) (2) IMs ( 7/ 3,... [Pg.284]

Influence of CYP2D6 Genotypes on Liver Transaminase Activity... [Pg.290]

When APOE and CYP2D6 genotypes are integrated in bigenic clusters and the APOE plus CTP2D6-related therapeutic response to a combination therapy is ana-... [Pg.306]

Veefkind AH, Haffmans PM, Hoencamp E (2000) Venlafaxine serum levels and CYP2D6 genotype. Ther Drug Monit 22 202-208... [Pg.447]

Nebert DW, Dieter MZ (2000) The evolution of drngmetabolism. Pharmacology 61 124-135 O Reilly RL, Bogue L, Singh SM (1994) Pharmacogenetic response to antidepressants in a multicase family with affective disorder. Biol Psychiatry 36 467-471 Ozdemir V, Tyndale RF, Reed K, et al (1999) Paroxetine steady-state plasma concentration in relation to CYP2D6 genotype in extensive metabolizers. J Clin Psychopharmacol 19 472-475... [Pg.544]

Pretreatment blood samples for PCR-CYP2D6 genotyping (poor-metabolizer alleles) in selected patients (e.g., those with a history of super sensitivity/marked clinical response to other medications)... [Pg.98]

Jerling, M., Dahl, M.-L., °Aberg-Wistedt, A., Liljenberg, B., Lan-dell, N.-E., Bertilsson, L., and Sjoqvist, F. (1996) The CYP2D6 genotype predicts the oral clearance of the neuroleptic agents perphenazine and zuclopenthixol. Clin Pharmacol Ther 59 423-428. [Pg.338]

Dahl M-L, Bertilsson L, Nordin C. Steady-state plasma levels of nortriptyline and its 10-hydroxy metabolite relationship to the CYP2D6 genotype. Psychopharmacology 1996 123 315-319. [Pg.68]

Morita S, Shimoda K, Someya T, Yoshimura Y, Kamijima K, Kato N. Steady-state plasma levels of nortriptyline and its hydroxylated metabolites in Japanese patients impact of CYP2D6 genotype on the hydroxylation of nortriptyline. J Clin Psychopharmacol 2000 20 141-149. [Pg.68]

Suzuki A, Otani K, Mihara K, Yasui N, Kaneko S, Inoue Y, Hayashi K. Effects of the CYP2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients. Pharmacogenetics 1997 7 415—418. [Pg.68]

Roh H-K, Chung J-Y, Oh D-Y, Park C-S, Svensson J-O, Dahl M-L, Bertilsson L. Plasma concentrations of haloperidol are related to the CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients. Br J Clin Pharmacol 2001 52 265-271. [Pg.69]

Lim HS, Lee HJ, Lee KS, Lee ES, Jang IJ, Ro J (2007) Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer. J Clin Oncol 25 3837-3845... [Pg.139]

Madlensky L, Natarajan L, Tchu S, Pu M, Mortimer J, Flatt SW, Parker BA, Wu AHB, Pierce JP (2010) Tamoxifen metabolite concentrations, CYP2D6 genotype and breast cancer outcomes. J Clin Oncol 89(5) 718-725... [Pg.139]

Borges S, Desta Z, Li L, Skaar TC, Ward BA, Nguyen A, Jin Y, Storniolo AM, Nikoloff DM, Wu L, Hillman G, Hayes DF, Stearns V, Flockhart DA (2006) Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism implication for optimization of breast cancer treatment. Clin Pharmacol Ther 80 61-74... [Pg.139]

Borges S et al (2006) Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism implication for optimization of breast cancer treatment. Clin Pharmacol Ther 80 61-74... [Pg.239]

Coller JK et al (2002) The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver. Br J Clin Pharmacol 54 157-167... [Pg.246]

See other pages where CYP2D6 genotype is mentioned: [Pg.51]    [Pg.103]    [Pg.455]    [Pg.153]    [Pg.217]    [Pg.284]    [Pg.285]    [Pg.285]    [Pg.288]    [Pg.290]    [Pg.307]    [Pg.192]    [Pg.533]    [Pg.634]    [Pg.212]    [Pg.59]    [Pg.60]    [Pg.64]    [Pg.67]    [Pg.136]    [Pg.137]    [Pg.225]    [Pg.226]   
See also in sourсe #XX -- [ Pg.23 ]



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