Cyclometallated chiral palladium complexes

Ort/ o-cyclometallated palladium complexes discussed in Section 2.2.2 have found another very important application as chiral templates that promote Diels-Alder and other reactions. This chemistry has been developed by Leung and co-workers and has allowed the synthesis of an impressing number of mono- and diphosphines bearing P-stereogenic atoms with peculiar scaffolds... 

P-chiral dibenzophosphole oxide (52a) (Scheme 14) shows liquid crystalline behaviour [52], a property that is of interest in the area of electro-optical displays [53]. Chiral resolution of (52a) was achieved by column chromatographic separation of the diastereoisomers obtained following coordination of the o -benzophosphole (52b) to chiral cyclometallated palladium(II) complexes [52]. Notably, the presence of a stereogenic P-centre is sufficient to generate a chiral cholesteric phase. 

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