Cyanide poisoning management

Cyanide poisoning is treated with attention to airway and cardiopulmonary management. Cyanide poisoning is treated with a specific antidote of amyl nitrite perles, sodium nitrite, and sodium thiosulfate. 

Geller, R.J., Barthold, C., Saiers, J.A., Hall, A.H. (2006). Pediatric cyanide poisoning causes, manifestations, management, and rmmet needs. Pediatrics 118 2146-58. 

Holland, M. A., Kozlowski, L. M. (1986). Clinical features and management of cyanide poisoning. Clinical Pharmacology, 5, 737-741. 

Maduh EU, Porter DW and Baskin SI (1993). Calcium antagonists. A role in the management of cyanide poisoning. Drug Safety, 9, 237-248. 

Cyanide forms a stable complex with the ferric ion of cytochrome oxidase enzymes, inhibiting cellular respiration. What is the connection between the management of cyanide poisoning and the drugs amyl nitrite and nitroprusside The Skill Keeper Answer appears at the end of the chapter. 

Antidotes for cyanide poisoning are effective only when administered immediately. The medical management procedures include inhalation of amyl nitrite followed by intravenous administration of about 300 mg sodium nitrite over two to four minutes and... 

Hall AH, Rumack BH. Management of cyanide poisoning. Ann Emerg Med. 1988 17 108-109. 

J.H. Wolfsie, C.B. Shaffer, Hydrogen cyanide—hazards, toxicity prevention and management of poisoning. J. Occup. Med. 1 28, 1959. 

Hall, A.H. and Rumack, B.H., Cyanide and related compounds, in Clinical Management of Poisoning and Drug Overdosage, Third Edition, Haddad, L.M., Shannon, M.W., and Winchester, J.F., Eds., Saunders, Philadelphia, PA, 1998, pp. 899-905. 

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