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CXCR4-Knockout Mice

3 Role in Embryonic Development Phenotypes of CXCLl 2 and CXCR4-Knockout Mice [Pg.244]

A further interesting phenotype identified in SDF-1/CXCR4 knockout mice is a deficiency in blood vessel development, initially observed in the gastrointestinal system (Tachibana et al. 1998). Consistent with such observations, CXCR4 receptors have been shown to be expressed by hemangioblasts, the earliest common precursor to hematopoietic and endothelial stem cells, found in yolk sac... [Pg.198]

See other pages where CXCR4-Knockout Mice is mentioned: [Pg.195]    [Pg.195]    [Pg.196]    [Pg.196]    [Pg.197]    [Pg.198]    [Pg.198]    [Pg.166]    [Pg.13]    [Pg.176]    [Pg.168]    [Pg.242]    [Pg.245]    [Pg.163]    [Pg.171]    [Pg.164]    [Pg.17]    [Pg.250]   


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