Cryogenic Zone Reactor

This method of low-temperature, direct fluorination involves very precise control of fluorine concentrations during the reaction, and initial high dilution of the fluorine with helium. The reaction of elemental fluorine with organometallic compounds is conducted (27) in a cryogenic-zone reactor (see Fig. 8) at temperatures in the range of - 78 to... 

LaMar direct fluorination (see p. 2) of ethyl acetate in a four-zone cryogenic reactor (lowest temperature —100 °C) provides the trifluoroacetates CF3 C02 C2F6 and CF3-C02-CHF-CF3 in 5 and 20% yield, respectively, after isolation by g-l.c. " apparently fluoride ion readily initiates decomposition of these esters according to F" + CFa COs-CFX CFsCFa COF -I- CFs-CFX-Q- -> F -I-CFa CXO (X = H or J). 

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