Creatine Kinase M CKM

Myl3 is an essential light chain of the myosin molecule expressed predominantly in the cardiac and skeletal muscle (Schiaffmo and Reggiani, 2011). Myosin is a six-subunit mechanochemical enzyme that consists of two heavy-chain 

TABLE 26.1 Circulating Biomarkers of Drug-Induced Skeletal Muscle Injury with Evidence of Potential Utility in Drug Development 

Protein Creatine kinase Serum Enzymatic Reviewed in Brancaccio et al. (2010) 

Fatty acid-binding Serum or plasma Immunoassay Pritt et al. (2008), Tonomura et al. 

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