Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Coupling reactions continuous-flow microreactor

Metal-catalyzed cross-couplings are key transformations for carbon-carbon bond formation. The applicability of continuous-flow systems to this important reaction type has been shown by a Heck reaction carried out in a stainless steel microreactor system (Snyder et al. 2005). A solution of phenyliodide 5 and ethyl acrylate 6 was passed through a solid-phase cartridge reactor loaded with 10% palladium on charcoal (Scheme 2). The process was conducted with a residence time of 30 min at 130°C, giving the desired ethyl cinnamate 7 in 95% isolated yield. The batch process resulted in 100% conversion after 30 min at 140°C using a preconditioned catalyst. [Pg.10]

See other pages where Coupling reactions continuous-flow microreactor is mentioned: [Pg.70]    [Pg.46]    [Pg.615]    [Pg.317]    [Pg.79]    [Pg.16]    [Pg.267]    [Pg.120]    [Pg.132]    [Pg.69]    [Pg.1256]    [Pg.1482]    [Pg.521]    [Pg.565]    [Pg.567]    [Pg.718]    [Pg.119]    [Pg.146]    [Pg.297]    [Pg.156]    [Pg.173]    [Pg.213]    [Pg.220]    [Pg.41]    [Pg.1116]   


SEARCH



Continuous flow

Continuous microreactors

Continuous reactions

Continuous-flow microreactor

Continuous-flow reaction

Flow microreactor

Flow-coupling

© 2024 chempedia.info