Costic acid

Costic acid, C15H2.2O2, is a free acid isolated from costus root oil. It is an unsaturated bicyclic acid of specific gravity 1 0501. It forms a. methyl ester, boiling at 170° to 175° at 11 mm. 

Costussaure, /. costic acid, costusic acid. Cotorindef/. cqto bark. 

Cryptomeridiol (227) is a fully saturated eudesmane from heartwood of Cryptomeria japonica (381). From the heartwood of red sandal (Pterocarpus san-talinus) a number of eudesmanes have been isolated, of which pterocarpdiolone (228) may be mentioned (246). Costic acid (229), a eudesmane acid, is present in costus root oil (30). Laevojunenol (230) from vetiver oil (Vetiveriazizanioides) of North Indian origin is an example of e t-eudesmane derivative (345). Of the many presently known eudesmanolides only a few have been isolated from woody parts of plants (+)-dihydro-/8-cyclocostunolide (231) was obtained from trunkwood of Moquinea velutina (146). 

Bawdekar A S, Kelkar G R 1965 Terpenoids. LXVIII. Structure and absolute configuration of costic acid, a new sesquiterpene acid from costus root oil. Tetrahedron 21 1521-1528... 

Root contains inulin (up to approx. 45%) polyacetylenes (0.001-0.002%, dry-weight basis) consisting mainly of 1,1 l-tridecadiene-3,5,7,9-tetrayne and 1,3,1 l-tridecatriene-5,7,9-triyne arctic acid and lappaphens a and b (acetylenic acids containing S) volatile acids (acetic, propionic, butyric, isovaleric, 3-hexenoic, 3-octenoic, costic, etc.) and nonhydroxy acids (lauric, myristic, stearic, palmitic, etc.) a... 

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