Cost function, test molecules

So the obvious question is this Why has the application of enantioselective catalysis to the fine chemicals industry, of potentially great economic and environmental interest, not been widely pursued on large scale It is true that different issues must be addressed firstly there is the cost of the chiral catalyst, but other problems must also be considered, such as general applicability many of the very selective catalysts have been developed for reactions with selected model substrates but not tested on differently functionalized molecules. In addition, for many catalysts little information is available on catalyst selectivity, ac-... 

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