Corydalis decumbens

Corydalis decumbens (Thunb.) Pers. Xia Tian Wu (aerial part) Protopine, bulbocapnine, d-tetrahydropalmatine.33-240 Toxic if overdosage. Relieve pain after bone fractures, antihypertensive, antirheumatic. 

Valeriana altemifolia, V. amurensis, V. fauriei, V. subbipinnatifolia Corydalis decumbens Stephania tetrandraq Sagittardia sagittifolia... 

Corydalis decumbens (Papaveraceae) jcps 4,57 95 Corydalis linarioides (Papaveraceae) yhhp 16,798 81 Corydalis scouleri (Papaveraceae) jnp 45,105 82 Fumaria parviflora (Papaveraceae) ojc 14,217 98... 

The plant Corydalis decumbens (Thunb.) Pers. (Papaveraceae) and the crude alkaloid fraction separated from the plant have been used in folk medicine in China to treat hypertension, hemiplegia and pseudomyopia. Several isoquinoline alkaloids such as berberine, bicuculine, bulbocapnine, jatrihizine, palmatine, tetrahydropalmatine and minor new alkaloids decumbenine, decumbenine B and decumbenine C were separated from the alkaloid fraction of the plant by repeated chromatography on silica-gel column. The structure of decumbenine 2-1, decumbenine B 2-2 and decumbenine C 2-3 are determined by spectral analyses and comparison with known isoquinoline alkaloids (Scheme 2). 

There are more than 700 aporphine alkaloids isolated, and they have been reviewed by Guinaudeau et al. [2—6]. Typical examples of this type of alkaloid are magnoflorine, isolated from the stems and leaves of Epimedium macranthum var. violaceum (Berberidaceae), domesticine from the fruits of Nandina domestica (Berberidaceae), nuciferine from the seeds of N. nudfera (Nymphaeaceae), and bulbocapnine isolated from the tubers of Corydalis decumbens (Fumariaceae). 

Shen Y, Han C, Jiang Y, Zhou X, Zhu Z, Lei X. Rapid quantification of four major bioactive alkaloids in Corydalis decumbens (Thunb.) Pers. by pressurised liquid extraction combined with liquid chromatography-triple quadrupole linear ion trap mass spectrometry. Talanta 2011 84 1026-31. 

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