Ovine corticotropin releasing factor

H-Asp-Phe(4-Tmd)-OMe ovine corticotropin releasing factor (oCRF) solution Boc, iBuOCOCl ... [Pg.113]

Anonymous. Corticorelin ACTH RF, corticoliberin, corticotrophin-releasing hormone, corticotropin-releasing factor, human corticotropin-releasing hormone, ovine corticotrophin-releasing factor, Xerecept. Drugs R D 2004 5(4) 218-9. [Pg.3]

Swanson LW, Sawchenko PE, Rivier R, Vale WW (1983) Organization of ovine corticotropin-releasing factor immunoreactive cells and fibres in the rat brain an immunoimmunohistochemical study. Neuroendocrinol 36 165-186. [Pg.519]

Sueiras-Diaz J, Coy DH, Vigh S, Redding TW, Huang WY, Torres-Aleman I, Schally AV. Synthesis and biological properties of ovine corticotropin-releasing factor (CRF). Life Sci. 75. 1982 31 429-435. [Pg.2207]

Scheme 8 TBTU-Mediated SPPS of Ovine Corticotropin Releasing Factor (oCRF)l l...

While the existence of corticotropin-releasing factor (CRF) was first proposed in 1955 it took 26 years to develop the isolation (RP-HPLC) and sequencing tools (microsequencing) that led to its characterization in 1981.P l First isolated from ovine hypothalanni,P l CRF was subsequently characterized from rat hypothalami P l the identical structure was deduced for human CRF (hCRF) on the basis of the cDNA sequence of the hCRF precursor gene.P CRF plays a major role in the maintenance or restoration of homeostasis by regulating the activity of the hypothalamic-pituitary-adrenal (HPA) axis.b°l Its first synthesis stretched the limits of SPPS capabilities and of preparative HPLC.P l... [Pg.811]

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