Cortex tissue oxygen tension

Kreisman NR, Sick TJ, La Manna JC, Rosenthal M. Local tissue oxygen tension-cytochrome a,a3 redox relationships in rat cerebral cortex in vivo. Brain Res 1981 218 161-174. 

The quantity of oxygen transported per unit of time by convection to the brain is determined by the blood flow rate, the oxygen capacity, the oxygen affinity of blood, and the arterial oxygen tension. Under normal conditions the mean overall blood flow rate in cerebral tissue of dogs, monkeys, and humans ranges between 50 and 65 ml/100 g-min (8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18). Specific measured mean values of 80 to 110 ml/100 g-min were determined for cerebral cortex (18,19, 20, 21, 22, 23, 24, 25, 26, 27), and 15 to 25 ml/100 g-min were measured for white matter (20, 23, 26). 

In this study a simulation of such processes for various arrangements of capillaries was performed to attain a better understanding of oxygen supply conditions in the brain cortex. Oxygen tension values were calculated for steady-state conditions by numerical solution of partial differential equations for different capillary-tissue systems. The analysis helps to explain the experimental results obtained from the microstructure of rat... 

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