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Cornea drug residence time

The limited mixing in the post lens tear film between the lens and the cornea leads to a residence time of more than 30 min for drugs released from the lenses. ... [Pg.1183]

The main challenge in ocular delivery is to increase the bioavailability of the drug and its residence time in the cornea, conjunctiva, and epithelia. Nanoscale polymers such as dendrimers can contribute to sustained release of encapsulated drugs at these sites. PAMAM dendrimers have been employed as ophthalmic vehicles in ocular delivery systems with pilocarpine nitrate and tropicamide (Vandamme and Brobeck 2005). [Pg.1698]

See other pages where Cornea drug residence time is mentioned: [Pg.91]    [Pg.308]    [Pg.1202]    [Pg.442]    [Pg.309]    [Pg.504]    [Pg.513]    [Pg.539]    [Pg.132]    [Pg.369]    [Pg.478]    [Pg.480]    [Pg.1348]    [Pg.1352]    [Pg.33]    [Pg.1195]    [Pg.285]    [Pg.476]    [Pg.1095]    [Pg.1168]    [Pg.1201]    [Pg.223]    [Pg.202]    [Pg.41]    [Pg.204]    [Pg.202]    [Pg.164]    [Pg.444]    [Pg.445]    [Pg.592]    [Pg.149]    [Pg.166]    [Pg.167]    [Pg.530]    [Pg.371]   
See also in sourсe #XX -- [ Pg.340 ]



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