Copper salicylate

Zinc oxide in conjunction with one or more conventional ballistic modifiers-lead stearate, lead acetophthalate, lead-P-resorcylale and basic copper salicylate etc. Propellants exhibit good quality plateau burning over a useful pressure range for a wide range of burn rates [241]. 

COPPER SULFATE GIVES THE GREEN COPPER SALICYLATE. 

Hangartner used a preparation of copper salicylate known as Permalon (made from 12.5 mM sodium salicylate and 0.04 mM Cu Cy to treat over 1100 patients over a 20 year period, with 89% showing benefit and few side effects. Unfortunately this therapy was discontinued when he retired in 1970.24... 

Basic Copper Salicylate (Monobasic Copper Salicylate). According to Satriana (Ref 2),... 

Satriana, Preparation of Analytically Pure Monobasic Copper Salicylate , PATR 2023 (1971)... 

However, Oberley and Buettner pointed out that all tumour cell lines have markedly decreased superoxide dismutase activity [355]. The marked decrease in manganese-dependent SOD activity is consistent with a decrease in aerobic metabolism and a decrease or only a modest increase in Cu-Zn SOD activity is consistent with an impaired response leading to transformation. As a result of the observed lowered SOD activities in tumour cells and an awareness of the SOD-mimetic activity of copper salicylate complexes, salicylate and other copper complexes were investigated as antitumour agents. 

E.E. Hac and I T. Gagalo, Copper Salicylate Complex. I Thermoregulatory effects. First World Conference on Inflammation Antirheumatics, Analgesics, and Immunomodula-tors. Venice, Italy, April 16-18, 1984. 

An interesting survey of copper salicylate, marketed as Permalon, is to be found in the reviews [60, 63, 71]. The structures of both the salicylate and aspirinate (acetylsalicylato) analogues [72, 73] confirm the expected dinuclear cage structure as in copper acetate (Compound 65, Chapter 6.2.3.) [74]. This study was initiated following the observation that active Finnish miners of copper were unaffected by rheumatism, despite the widespread incidence of the disease in the country. Purulent infections... 

Copper complexes also have demonstrated potential utility in treatment of arthritis. Copper salicylate (permalon) has been marketed but presently no other metal salts besides those of gold are in clinical use. The... 

W. Hangarter Copper-Salicylate in Rheumatoid Arthritis and Similar Diseases in Ref. 2, pp. 439—452. See Discussion. 

Ferrocene, copper salicylate and copper phthalo-cyanate... 

The authors examined the possibility of using a non-traditional method of vulcanisation of compounds based on cis-1,4-polyisoprene and fluororubber under dynamic conditions with the application of shear forces. Vulcanising systems based on a sulphur-containing system and copper salicylal iminate were employed. Data are given on the effect of the method of vulcanisation on the physical and mechanical properties of the vulcanisates. 6 refs. Articles from this journal can be requested for translation by subscribers to the Rapra produced International Polymer Science and Technology. 

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