Conversation group size

The results from the first study suggest rather clearly that conversation group sizes are limited at about four individuals (one speaker and three listeners) (Dunbar et al. 1995). Fig. 3 plots the cumulative frequency distributions for the number of individuals that a speaker can reach (i.e. conversation group size less one, since there is always only one speaker at any given moment per conversation Dunbar et al. 1995). All three datasets in the sample suggest that the number of listeners rapidly approaches an asymptotic value at around three. 

In a three-component polyurethane system with OH groups, wherein crosslinker is a triol, one finds them substantially more reactive than those of the macro-molecular diol. The hard clusters grow substantially larger, at relatively low conversions. Their size remains almost constant because all triol units have been used up in the reaction. In the opposite case, the lower reactivity of OH groups found in macromolecular diol compared with that of triol, the clusters remains small throughout the reaction and grows larger only at its end. 

Figure 4. The maximum group size for a conversation in which all members are able to clearly discriminate speech sounds spoken at normal voice levels by all speakers, plotted against speech interference levels. The lower line (for d = 100cm) is drawn by extrapolation from the other two lines, d is the inter-individual distance measured nose-to-nose between adjacent individuals on the circumference of the circle. Source redrawn from Cohen 1971 (Fig. 7.1)...

Dunbar, R.I.M., Duncan, N. Nettle, D. (1995). Size and structure of freely-forming conversational groups. Human Nature 6 67-78. 

Conversely, the size of the R1 group has less influence on the activity of the catalyst (see Figure 43). Nevertheless, in the case of R1 = aromatic ring, bulky groups in position 2 of the phenyl ring depress activity (see Figure 43).1129,1151... 

Classical bubbles do not exist in the vigorously bubbling, or turbulent fluidization regimes. Rather, bubbles coalesce constantly, and the bed can be treated as a pseudohomogenous reactor. Small bubble size improves heat transfer and conversion, as shown in Figure 5b. Increasing fines levels beyond 30—40% tends to lower heat transfer and conversion as the powder moves into Group C. 

Several clinical trials have been conducted with streptokinase adrninistered either intravenously or by direct infusion into a catheterized coronary artery. The results from 33 randomized trials conducted between 1959 and 1984 have been examined (75), and show a significant decrease in mortaUty rate (15.4%) in enzyme-treated patients vs matched controls (19.2%). These results correlate well with an ItaUan study encompassing 11,806 patients (76), in which the overall reduction in mortaUty was 19% in the streptokinase-treated group, ie, 1.5 million units adrninistered intravenously, compared with placebo-treated controls. The trial also shows that a delay in the initiation of treatment over six hours after the onset of symptoms nullifies any benefit from this type of thrombolytic therapy. Conversely, patients treated within one hour from the onset of symptoms had a remarkable decrease in mortaUty (47%). The benefits of streptokinase therapy, especially in the latter group of patients, was stiU evident in a one-year foUow-up (77). In addition to reducing mortahty rate, there was an improvement in left ventricular function and a reduction in the size of infarction. Thus early treatment with streptokinase is essential. 

The principle of equal reactivity as enunciated above asserts merely that all like functional groups remaining unreacted at any given stage of the process enjoy equal opportunities for reaction. It has not been stated that the level of reactivity (i.e., the velocity coefficient) necessarily remains constant as the reaction progresses. Indeed, the velocity coefficient for polyesterification has been shown to change as the reaction progresses from 0 to 80 percent conversion. Since monoesterifications exhibit a similar perturbance, it has been concluded that the size of the polymer molecules formed does not alter the course of the reaction hence the principle of equal reactivity is not violated. 

The same group has looked into the conversion of NO on palladium particles. The authors in that case started with a simple model involving only one type of reactive site, and used as many experimental parameters as possible [86], That proved sufficient to obtain qualitative agreement with the set of experiments on Pd/MgO discussed above [72], and with the conclusion that the rate-limiting step is NO decomposition at low temperatures and CO adsorption at high temperatures. Both the temperature and pressure dependences of the C02 production rate and the major features of the transient signals were correctly reproduced. In a more detailed simulation that included the contribution of different facets to the kinetics on Pd particles of different sizes, it was shown that the effects of CO and NO desorption are fundamental to the overall behavior... 

It is the tertiary amides that tend to be the most problematic in terms of proton NMR. They usually exhibit two rotametric forms, the relative proportion of each being determined by both electronic factors and by the relative sizes of the two groups, R1 and R2. Note this in no way implies that the rotameric forms of a tertiary amide could ever be physically separated as the inter-conversion rate between the two forms is generally in the order of seconds. A 50/50 ratio of rotamers is only guaranteed where R =R2 (as in the case of a primary amide where R1=R2=H). Consider the two compounds in Structures 6.14 and 6.15. 

In order to explore the generality of this new domino reaction the conversion of various primary amines with 2-341 and the cyclohexane analogue was investigated (Scheme 2.81). For example, the reaction proceeds with high yields when benzyl- or (2-phenylethyl)amine are used (entries 1 and 2). In comparison, sterically more hindered amines such as 2-butylamine produced much lower yield (entry 4) Furthermore, the reaction tolerates other functional groups, such as an unprotected hydroxyl group (entry 5), and variation of the enone ring size is possible (entries 6 and 7). More recent results have revealed that the addition of Sn(OTf)2 or In(OTf)2 makes the transformation more reliable. 

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