Continuous drug manufacturing

Figure 11.29 Continuous drug manufacturing prototype in an MIT chemical engineering laboratory [80].

MIT, Continuous drug manufacturing offers speed, lower costs, http //web.mit. edu/newsoffice/2012/manufacturing-pharmaceuticals-0312.html (last accessed August 2012). 

The FDA also has statutory authority to request the Department of Justice to seek a court injunction against continued violations of the law by a prescription drug manufacturer or distributor. FDA has had mixed results in attempting to obtain injunctions from the courts, who realise that an injunction can shut down a company entirely or subject it to arbitrary demands by... 

The companies that supply intermediates to organized crime continue to do so with impunity. I spoke with a major supplier to global organized crime a few years ago. They supply illegal drug manufacturing syndicates with multi tons of intermediates. The sales person laughed when I mentioned the word ethics. 

The current post-marketing surveillance system in the United States is a multifaceted, international process involving the FDA, drug manufacturers, healthcare providers, and patients. Whereas the FDA is strengthening the current system, its success will still rely heavily on the submission of spontaneous reports. Therefore, healthcare providers need to be continually reminded of the value of reporting ADEs. 

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