Construction of pharmacokinetic sketches profiles

Relationships between pharmacokinetic terms can be demonstrated by the construction of 

A pharmacokinetic calculation is not complete unless both the number and the unit have been determined. If the unit that is determined is not the unit expected, this situation can evenalertyou too mistake in the calculation. For example, in a problem where a dose of drug is being calculated and the unit comes out to be something other than mass units, you would be well advised to perform the calculation again with particular care. 

Area under Cp versus time curve (pg/mL) h pgmL h 

Retain units throughout the whole calculation and present them with the numerical answer. 

Some quantities are unitless (e.g. fraction of drug absorbed, F). Unitless numbers generally arise from the fact that units of ratios cancel. For example, F is the ratio (AUC)oral/(AUC)iv. 

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