Considerations of Local Anaesthetic Drug Substances

CHEMICAL CONSIDERATIONS OF LOCAL ANAESTHETIC DRUG SUBSTANCES 

The presenee of the anaesthesiophoric moiety in cocaine, discovered in the year 1880, employed profusely as a vital loeal anaesthetie in various surgical procedures by virtue of its ability to cause anaesthesia by blocking nerve conductance, ultimately paved the way for the synthesis of thousands of new compounds known as local anaesthetics . However, about twenty such compounds have gained recognition and congnizance as local anaesthetics in the therapeutic armamentarium. 

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