Conjugation of glucuronic acid

Urinary diterpenes excretion. Absorption and excretion of the cholesterol-raising coffee diterpenes cafestol and kahweol were observed in nine healthy patients with ileostomies. Ileostomy effluent was collected for 14 hours, and urine was collected for 24 hours. Approximately 70% of the ingested cafestol and kahweol was absorbed. Only small part of the diterpene was excreted as a conjugate of glucuronic acid or sulphate in urine, mean excretion was 1.2% of the ingested amount for cafesterol and 0.4% for kahweol . 

The domestic fowl has an unusual mechanism for handling benzoic acid. This acid is conjugated with ornithine, instead of glycine, and ornithuric acids are excreted after administration of many aromatic acids. Until recently, it was not known whether or not the fowl could synthesize conjugates of glucuronic acid, but this information has now been supplied by Sperber.108 He has shown that, in the hen, intramuscular injection of... 

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