Computer-assisted sperm analysis

Song L, Wang YB, Sun H et al (2008) Effects of fenvalerate and cypermethrin on rat sperm motility patterns in vitro as measured by computer-assisted sperm analysis. J Toxicol Environ Health A 71 325-332... 

Sperm analysis is optional (1). The most precise method uses computer assisted sperm analysis (CASA), e.g., Hamilton-Thorne IVOS. Sperm analysis, while not obligatory according to ICH S5(R2), should be performed because one ofthe major mechanisms... 

Kime, D.E., Ebrahimi, M., Nysten, K., Roelants, I., Rurangwa, E., Moore, H.D.M. and Ollevier, F. (1996) Use of computer assisted sperm analysis (CASA) for monitoring the effects of pollution on sperm quality of fish application to the effects of heavy metals. Aquatic Toxicology, 36, 223-237. 

The computer-assisted sperm analysis (CASA) measures the effects of chemicals on spermatozoa viability, motility, velocity, motion, and morphology allowing to characterize reversible and irreversible damages to the mature sperm. It is a well-established... 

Briggs, G.B., W.A. Price, A.F. Walsh, K.R. Still, and W.K. Alexander. 1999. Evaluation of JP-8 jet fuel potential to produce male reproductive toxicity using the computer-assisted sperm analysis system. Teratology 59(6) 415. 

Toth GP, Stober JA, George EL, Read EJ, Smith MK (1991a) Sources of variation in the computer-assisted motion analysis of rat epididymal sperm. Reprod Toxicol, 5 467-495. 

Harper, M.J.K. (1994). Gamete and gote transport, in The physiology of Reproduction (E. Knobil and J.D. NerU, eds.), pp. 123-187. Raven Press, New York. Hong, C.Y., Chao, H.T., Tsai, K.L. and Ng, H.T. (1991). Evaluation of human sperm motflity by means of transmembrane migration method and computer-assisted semen analysis—a comparison study. Andrologia 23, 7-10. 

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