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Computational toxicology systems biology

It is unlikely that any one program will ever become a complete computational toxicology toolbox. Rather, it is more likely that certain predictive software will be used for specific applications, while more general applications will be used to create relevant datasets for multiple uses. Systems biology pathway software, in concert with metabolite prediction, pharmacokinetics, and ADME software will be critical in reducing cost and time necessary for the development of new pharmaceuticals [49],... [Pg.743]

Bromaghin, J.F. and R.M. Engeman. 1989. Head to head comparison of SAS and ASTM-proposed probit computer programs. In Acjuatic Toxicology and Environmental Fate, Vol. 11, ASTM STP 1007. G.W. Suter and M.A. Lewis, Eds. American Society for Testing and Materials, Philadelphia, PA, pp. 303-307. Brooks, D.R., J. Collier, B.A. Mauer, J.D.H. Smith, and E.O. Wiley. 1989. Entropy and information in evolving biological systems. Biol. Philos. 4 407—432. [Pg.67]

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