Compound Selection 10 K Validation Set

One advantage of evaluating a 10 k selection before running the full HTS is that the set can be used to ensme the quality of the screen and to estimate the 

Single-concentration effect Can later be correlated with the HTS output to ensure quality of the screen 

Early hits Can be used as tool compounds for further evaluation, e.g. counterscreen or performance of secondary screens 

Possible off-target or technology- The assays propensity to identify off-target-related hits or 

Potency Provides information in which potency range compounds will be identified by the HTS 

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