Complex biomedical systems

Krejcar O, Janckulik D, Motalova L (2009) Complex Biomedical System with Biotelemetric Monitoring of life Funcdons. In lYoceedings of the IEEE Eurocon 2009, May 18-23, 2009, SL Petersburg, Russia, pp. 138-141. DOI 10.1109/EURCON.2009.5167618... 

Finally, Section 2.4 analyses a simplified model of a bursting pancreatic /3-cell [12]. The purpose of this section is to underline the importance of complex nonlinear dynamic phenomena in biomedical systems. Living systems operate under far-from-equilibrium conditions. This implies that, contrary to the conventional assumption of homeostasis, many regulatory mechanisms are actually unstable and produce self-sustained oscillatory dynamics. The electrophysiological processes of the pancreatic /3-cell display (at least) two interacting oscillatory processes A fast process associated with the K+ dynamics and a much slower process associated with the Ca2+ dynamics. Together these two processes can explain the characteristic bursting dynamics in the membrane potential. 

In this section, a set of elementary structures is investigated. These components are essentially embedded in more complex electromagnetic compatibility devices (EMC) devices regarding microwave instrumentations, miniaturized packaging layouts in communication ensembles, power managing tools, and biomedical systems for the estimation of hazardous health effects. Since, their profile may lead to complicated field patterns, it is anticipated that HO FDTD operators will provide the most sufficient results. 

Owing to their unique chemical and physical structure, carbon-based NMs are potential candidates for a variety of biomedical applications, including early imaging, NIR photothermal therapy, photoacoustic imaging, and drug delivery. When these NIR NMs are introduced into complex biological systems, the related risk assessment is of considerable importance to both human and environmental health. Based on current studies, we mainly discuss the in vitro and in vivo toxicity of CNTs and graphene. 

Some aspects concerning micellar nanoparticles obtained by complex formation will then shortly be reviewed, as well as some typical features related surface modification of biomedical systems. 

The coupling of encapsulation technologies with cell culture techniques permits the extended use of these bioreactors with complex tissue systems such as islet clusters. Existing reactor systems are also useful in obtaining the basic transport and reaction kinetics parameters necessary to design the novel devices required for biomedical applications. In summary, the relevance of this work to the biotechnology and health care-based industries is in the development, of artificial organ systems, extra-corporeal devices to... 

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