Photoacoustic imaging

Photoacoustic imaging method is useful for the analysis of localization of various components in two-dimension and photoacoustic method has one more advantage that it can be applied to the non-destructive depth-profiling. Thus, in future, 3-dimensional analysis should be possible by this method. For the development of this possibility, the model experiments were performed. 

Photoacoustic imaging (PAI) Ultrasound ICG-embedded ormosil nanoparticles, Au-nanoshells Skin and other epithelia, breast cancer detection ... 

Mallidi, S., et al. Multiwavelength photoacoustic imaging and plasmon resonance coupling of gold nanoparticles for selective detection of cancer. Nano Letters 9(8), 2825-2831(2009)... 

Figure 10.8 Photosensitizer (Ce6)-loaded plasmonic gold vesicles (GVs) for trimodality fluorescence/thermal/photoacoustic imaging guided synergistic photothermal/photodynamic cancer therapy. (Reproduced with permission from S. Wang, P. Huang, L. Nie, R. Xing, D. Liu, Z. Wang, J. Lin, S. Chen, G. Niu, G. Lu and X. Chen, Adv. Mater., 2013,25,3055. Copyright (2013) American Chemical Society. )...

Owing to their unique chemical and physical structure, carbon-based NMs are potential candidates for a variety of biomedical applications, including early imaging, NIR photothermal therapy, photoacoustic imaging, and drug delivery. When these NIR NMs are introduced into complex biological systems, the related risk assessment is of considerable importance to both human and environmental health. Based on current studies, we mainly discuss the in vitro and in vivo toxicity of CNTs and graphene. 

R. G. M. Kolkman, E. Hondebrink, W. Steenbergen, and F. F. M. de Mul, In Vivo Photoacoustic Imaging of Blood Vessels Using an Extreme-Narrow Aperture Sensor, IEEE ]. Set Top. Quantum Electron., 9,343 (2003). 

E. Z. Zhang and P. C. Beard, 2D Backward-Mode Photoacoustic Imaging System for NIR (650-1200 nm) Spectroscopic Biomedical Applications, Proc. SPIE 6086 (2006). 

L. Chao-Kang et al.. Nanorod-based flow estimation using a high-frame-rate photoacoustic imaging system. Journal of Biomedical Optics, 12(6), 064006 (2007). 

Pan D, Kim B, Wang LV, Lanza GM. A brief account of nanoparticle contrast agents for photoacoustic imaging. WIREs Nanomed Nanobiotechnol 2013 5 517 3. 

Li Kai, and Liu Bin. Polymer-encapsulated organic nanoparticles for fluorescence and photoacoustic imaging. Chem. Soc. Rev. 43 (2014) 6570-6597. 

J.V. Jokerst, A.J. Cole, D. Van de Sompel, S.S. Gambhir, Gold nanorods for ovarian cancer detection with photoacoustic imaging and resection guidance via Raman imaging in living mice. ACS Nano 6, 10366 (2012)... 

Allen, T.J. and Beard, P.C. (2005) Pulsed near-infrared laser diode excitation system for biomedical photoacoustic imaging. Optics Letters, 31, 3462-4. 

Photoacoustic imaging of early inflammatory response using gold nanorods, K. Kim, S.-W. Huang, S. Ashkenazi, M. O Donnell, A. Agarwal, N. A. Kotov, M. F. Denny, and M. J. Kaplan, Appl. Phys. Lett., 2007, 90, 223901. 

Dual wavelength laser diode excitation source for 2D photoacoustic imaging, T. J. Allen and P. C. Beard, Proc. SPIE, 2007, 6437, 64371U/1. 

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