Peripheral compartment

Cytosolic compartments (peripheral pool internal pool) equilibrate rithin 4 min. with exogenous L-Phe. Tentative separation of two cytosolic pools accounts for the rapid pulse labelling of proteins even at very low concentrations of exogenous L-Phe in contrast to the lacking labelling under chase conditions. Both pools cannot be discriminated by the kinetic experiments (Pig. 2). 

Circular Clarifiers Circular units are available in the same three basic types as single-compartment thickeners bridge, center-column, and peripheral-traction. Because of economic considerations, the bridge-supported type is limited generally to tanks less than 20 m in diameter. 

Golgi apparatus A system of flattened membrane-bounded vesicles often stacked into a complex. Numerous small vesicles are found peripheral to the Golgi and contain secretory material packaged by the Golgi. Involved in the packaging and processing of macromolecules for secretion and for delivery to other cellular compartments. 

This model is an extension of the one-compartment model for intravenous injection (Section 39.1.1) which is now provided with a peripheral buffering compartment which exchanges with the central plasma compartment. Elimination occurs via the central compartment (Fig. 39.12). The model requires the estimation of the plasma volume of distribution and three transfer constants, namely for... 

Description of the model. The Leggett Model includes a central compartment, 15 peripheral body compartments, and 3 elimination pools, as illustrated in Figure 2-9. Transport of lead between... 

As already mentioned, macular zeaxanthin comprises two stereoisomers, the normal dietary (3/(,37()-/caxanthin and (3f ,3 S)-zeaxanthin(=(meyo)-zeaxanthin), of which the latter is not normally a dietary component (Bone et al. 1993) and is not found in any other compartment of the body except in the retina. The concentration of (tneso)-zeaxanthin in the retina decreases from a maximum within the central fovea to a minimum in the peripheral retina, similar to the situation with (3/ ,37 )-zeaxanthin. This distribution inversely reflects the relative concentration of lutein in the retina and gave rise to a hypothesis (Bone et al. 1997) that (meso)-zeaxanthin is formed in the retina from lutein. This was confirmed by an experiment in which xanthophyll-depleted monkeys had been supplemented with chemically pure lutein or (3/ ,37 )-zeaxanthin (Johnson et al. 2005). (Meyo)-Zeaxanthin was exclusively detected in the retina of lutein-fed monkeys but not in retinas of zeaxanthin-fed animals, demonstrating that it is a retina-specific metabolite of lutein only. The mechanism of its formation has not been established but may involve oxidation-reduction reactions that are mediated photochemically, enzymatically, or both. Thus, (meso)-zeaxanthin is a metabolite unique to the primate macula. 

Peripheral Compartment Third Compartment A Renal and other extra-hepatic clearances... 

This chapter provides a short review of peripheral nerve diseases. Diseases that involve motor neurons, the presyn-aptic compartment of neuromuscular junctions, or the enteric nervous system are also discussed. 

In vitro data cannot predict the volume of distribution in central or in peripheral compartments. 

A form of multicompartmental modelling in which there is a central compartment to which a stated number of peripheral compartments are connected. 

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