Combination alkylation

Beside these compounds which combine alkyl chains and perfluorinated chains at opposite ends of a cyclic unit, there are several examples of liquid crystalline materials combining a single aromatic ring with a single semiperfluorinated alkyl chain or with two or three Rp-chains in close proximity. 

Alkyl Silanes or Alkyl Silicanes are compds combining alkyl groups with silicon or silicon hydrides, eg, methylsilaneCHjSiH, dimethyl silane (CH,),SiH, trimethyl silane (CH,),SiH, tetramethylsilane (CH,)4Si and yinylsilane (CH, CH)SiH,. They are very... 

Two important premises made were first, that the alkylation was an irreversible reaction with transalkylation a separate and independent reaction, and second, that the reaction rate of molecular ethylene in the liquid was not rate controlling as long as the concentrations of the higher polyethylbenzenes were low. This allowed the kinetic constants for the transalkylation model to be evaluated from transalkylation data when the combined alkylation-... 

Sugimura H, Hanji T, Hayashi K, Takai O (2002) Surface potential nanopatteming combining alkyl and fluoroalkylsilane self-assembled monolayers fabricated via scanning probe hthog-raphy. Adv Mater 14 524-526... 

The Pd-catalyzed, LiHBEt3-mediated reductive desulfonylation of allylic sulfones is also used in the ligand-controlled stereoselective synthesis of dienes191 where it is possible to control the geometry of the diene by a proper selection of the palladium ligand as shown by the distribution of products 1 and 2 (Eq. 115). The method described herein is also applicable to the so-called integrated chemical processes , which allow the preparation of a wide variety of alkenes by combining alkylation of allylic sulfones and reductive desulfonylation in one pot.192,193... 

By manually combining alkyl-acrylates or alkyl-acrylamides with primary or secondary amines, researchers were able to synthesize over 700 lipidoids (lipid-like delivery molecules Figure 11). The choice of monomers in this library allowed investigators to systematically examine a number of structural parameters (1) alkyl chain length (2) an amide versus an ester linkage (3) amine diversity and (4) the effect of quaterniza-tion of the amine by reacting lipidoids with methyl iodide (Mel) post-synthesis. 

In 2010, Mongin and co-workers expanded this amino Li/Zn mixture model to a new combination alkyl/amino Li/Zn model, LiR/Zn(TMP)2 (1/1) [78]. NMR analysis and calculation indicated formation of the zincate LiZn(TMP)2R in these circumstances. Exceptionally, when (trimethylsilyl)methyllithium was used instead, the calculation showed that formation of a lithium zincate became unlikely and thus the reaction route may then be similar to that of the LiTMP/Zn(TMP)2 combination. Nevertheless, these zincates or base mixtures are also effective for deprotonation of arenes (Eq. 24). 

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