Comb, Brush-Block, Dendritic-Like Chimeras

2 Comb, Brush-Block, Dendritic-Like Chimeras 

The limitations in achieving true living polymerization conditions of NCAs have, in the past, rendered difficult the synthesis of more complex structures containing polypeptide chains, such 

The grafting-from approach was also employed in more recent studies. N-f r -butox-ycarbonyl-N -(2-methacryloyl)-l,3-diaminopropane was prepared by Zhang et al (2005) and polymerized by free-radical polymerization. The quantitative deprotection of the amine group was performed in a mixture of dichloromethane and trifluoroacetic acid. 

A polyamidoamine dendron (PAMAM) carrying a Boc-protected amine group was also synthesized by Harada et al. (2006 2009). The protective group was then removed 

Using similar methodology the synthesis of asymmetric PEO-b-(Dm-PBLG) and symmetric (Dm-PBLG)-b-PEO-b-(Dm-PBLG) hybrid copolymers having 2 (m = 0,1,2,3) PBLG 

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Controlled/living polymerization techniques in combination with living ROP of NCAs can lead not only to linear but also to nonlinear chimeras. In this section we will describe the materials synthesized according to their structure star, comb, brush-block, and dendritic-like chimeras. 

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