Column packings titania

K. Murayama, H. Nakamura, T. Nakajima, K. Takahashi, and A. Yoshida, Preparation and evaluation of octadecyl titania as column-packing material for high-performance liquid chromatography, Microchem. J. 49 (1994), 362-367. 

Fig. 5 Chromatograms obtained on four mixed oxide packing materials. Solute 1 = benzene 2 = dimethyl phthalate 3 = pyridine. Column packing material (a) silica-zirconia (b) silica-alumina (c) silica-titania (d) silica-magnesia (e) silica gel. Mobile phase, -hexane containing 1% methanol flow rate, 1 mL/min column temperature, ambient detection, UV 254 nm. (From Ref. [1].)...

A few applications have employed conventional packed columns, although recent developments in new thermally stable stationary-phase materials have generated a renewed interest and the temperature stability of the different stationary-phase materials has been reviewed by Claessens and van Straten [43]. The new materials have included stable metal oxide materials, based on zirconia (Figures 18-4 and 18-5) and titania [44, 45] and hybrid phases combining silica and methylene or ethyl bridges [46]. These have been applied in a number of applications to pharmaceutical compounds (Table 18-1). 

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