Colonic targeting pectin

The W-acetyl chitosans are the most interesting for controlled release. Galactosylated chitosan microspheres have been prepared. Production of more specific oligoglycoside-chain chitosan might develop into active targeting of specific tissues. Pectinate gel beads modified with trimethyl chitosan have been prepared and evaluated for colon targeted delivery of macromolecules. 

Pectin Novel colon-targeted drug delivery system Ravi et al. (2008), Khanlari and Dube (2013), and Ghaffari et al. (2007)... 

L.N.M. Ribeiro, A.C.S. Alcintara, M. Darder, P. Aranda, F.M. Araiijo-Moreira, and E. Ruiz-Hitzky, Pectin-coated chitosan-LDH bionanocomposite beads as potential systems for colon-targeted drug delivery, Int. J. Pharmaceut., 463,1-9,2014. 

A.M.J. Newton, and P. Lakshmanan, Effect of HPMC-E15 LV premium polymer on release profile and compression characteristics of chitosan/pectin colon targeted mesalcunine matrix tablets and in vitro study on effect of ph impact on the drug release profile. Recent... 

Jung J, Arnold RD, Wicker L (2013) Pectin and charge modified pectin hydrogel beads as a colon-targeted drug delivery carrier. Colloids Surf B Biointerfaces 104 116-121 Keplinger C, Sun J-Y, Foo CC et al (2013) Stretchable, transparent, ionic conductors. Science 341 984-987... 

Newton AMJ, Kaur B, Indana VL, Rajesh Kumar S. Chronotherapeutic drug delivery of pectin vs. guar gum, xanthan gum controlled release colon targeted directly compressed propranolol HCl matrix tablets. SAJ Pharma Pharmacol. 1 (2) 1-12,2014. 

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