Collander-type relationships

Muller s Relationship Muller [17] derived the following collander-type relationship for the monohydrophilic class of alkanols (C2-C6) ... 

It is known that the RPLC retention parameters are often strongly correlated to the analyte s distribution coefficient in organic solvent/ water. Generally, the relationship between liquid/liquid (LL) distribution and RPLC retention are of the form of the dimensionless Collander-type equations, e.g., see Eq. (15.21)... 

Roberts et al. criticized the attempts to predict permeabilities since permeability is the result of two processes, partitioning and diffusion [40], Therefore, instead of following the approach of Potts and Guy, Roberts et al. tried to find a predictive model for each of these processes separately. For the partitioning step they found a Collander-type linear relationship (Eq. 11) between the logarithms of the stratum corneum-water and the octanol-water partition coefficients with a high correlation coefficient (r2 = 0.839) ... 

Partition coefficients from different solvent systems can also be compared and converted to the octanol/water scale, as was suggested by Collander (116). He stressed the importance of the following linear relationship log 2 = a logPj + b. This type of relationship works well when the two solvents are both alkanols. However, when two solvent systems have varying hydrogen bond donor and acceptor capabilities, the relationship tends to fray. A classical example involves the relationship between log P values in chloroform and octanol (117,118). 

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