Collagens collagen-like families

COLLAGEN AND COLLAGEN-LIKE FAMILIES Collagen-hike Proteins... 

Collagen is the most abundant extracellular matrix protein family in vertebrates. Proteins in the collagen superfamily all have three polypeptide chains with the required -Gly-Xaa-Yaa- repeated sequence, where Xaa and Yaa are frequently proline and 4-hydroxyproline, respectively. At present, more than 30 molecular species of vertebrate proteins called collagen are classified into 28 types as type I, II, III,..., XXVIII. They are typically called type N collagen , or collagen N . In addition, there are many more collagen-like proteins that... 

Collectins are a family of C-type lectins that mediate host defense against pathogenic micro-organisms. Each collectin polypeptide is characterized by an N-terminal collagen-like region and a C-terminal C-type CRD [1]. Six members of the collectin family have been identified in vertebrates. Serum MBP, collectin-43 (CL-43) and conglutinin are plasma proteins, liver MBP is found exclusively in the liver and pulmonary surfactant proteins-A and -D (SP-A, SP-D) are associated with the surfactant that lines alveoli in the lung. 

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