Cross-linking collagen

Pyridinium species comprise collagen cross-links that are formed during bone remodeling by osteoblasts. These cross-links are released into the serum and excreted in... [Pg.318]

Collagen cross-links. Besides amide bonds between amino acids in the same a chain, bonds between amino acid side chains of different a chains can form "cross-links". These bonds originate from enzymatically-oxidized side chains of lysine and hydroxylysine residues. The oxidized residues react with other lysine and hydroxylysine residues, forming difunctional products. Reactions of such products with oxidized lysine or hydroxylysine yield trifunctional cross-links (Reiser et al., 1992). [Pg.8]

Collagen cross-links in dentin. AHLNL, didehydro-hydroxylysinonorleucine ADHLNL, didehydro-dihydroxylysinonorleucine LP, lysylpyridinoline HP,... [Pg.9]

Light N and Bailey AJ (1985) Collagen cross-links location of pyridinoline in type 1 collagen. FEES Lett 182, 503-508. [Pg.15]

Yamauchi M, Chandler GS and Katz EP (1992) Collagen cross-linking and mineralization. Excerpta Med Int Congr Ser 1002, 39-46. [Pg.16]

It is noteworthy that several of fhe above-mentioned mediators of discoloration have been found fo inhibif sfrepfococcal proliferation. In addition, collagen cross-linking caused by enzymatic and non-enzymat-ic browning or by tannage with tannins might render dentin less susceptible to proteolytic degradation. [Pg.38]

Rivera EM and Yamauchi M (1993) Site comparisons of dentin collagen cross-links from extracted human teeth. Arch Oral Biol 38, 541-546. [Pg.71]

Reduction and hydrolysis. Reduction was necessary to stabilize the acid-labile difunctional collagen cross-links by converting A-DHENE and A-HLNL into DHLNE and HLNL, respectively. [Pg.75]

The occurrence of four collagen cross-links in bovine dentin has been described previously (Linde and Robins, 1988 Walters and Eyre, 1983 Yamauchi et al., 1992) didehydro-hydroxylysinonorleucine (A-HLNL), didehydro-dihydroxylysinonorleucine (A-DHLNL), lysylpyridinoline (LP), and hydroxylysylpyridinoline (HP). In this investigation, only two of these established cross-links were purified HP (peak 111, fig. 1) and DHLNL (peakV-1-1). [Pg.86]

Ranta H (1978) Age-related changes in collagen cross-linking. Changes in bovine dentine and periodontal ligament and description of a new type of non-reducible cross-link. Proc Finn Dent Soc 74 (Suppl. II), 3-64. [Pg.93]

Scott JE, Qian R-G, Henkel W and Glanville RW (1983) An Ehrlich chromogen in collagen cross-links. Biochem J 209, 263-264. [Pg.94]

Shiraki, M., Kuroda, Y., Tanaka, S., Salto, M., Fukunaga, M., and Nakamura, T. (2008). Nonenzymic collagen cross-links induced by glycoxidation (pentosidine) predicts vertebral fractures. J. Bone Miner. Metab. 26, 93-100. [Pg.150]

Blanque R, Cottereaux C, Gardner CR (2001) Phasic production of urinary pyridinium crosslinks in mice the effect of ovariectomy. Calcif Tissue Int 68 102-108 Eyre DR (1995) The specificity of collagen cross-links as markers of bone and connective tissue degradation. Acta Orthop Scand Suppl 266 166-170... [Pg.252]

James IT, Perret D, Thompson PW (1990) Rapid assay for hard tissue collagen cross-links using isocratic ion-pair reversed-phase liquid chromatography. J Chromatogr 525 43-57... [Pg.252]

Kaufmann J, Mueller A, Voigt A et al. (2003) Hydroxypyri-dinium collagen crosslinks in serum, urine, synovial fluid and synovial tissue in patients with rheumatoid arthritis compared with osteoarthritis. Rheumatology 42 314-320 Knott L, Bailey AJ (1998) Collagen cross-links in mineralizing tissues a review of their chemistry, function, and clinical relevance. Bone 22 181-187... [Pg.252]

Cl. Calabresi, E., Lasagni, I., Franceschelli, F., de Leonardis, V., Becorpi, A., etal., Comparison of immuno- and HPLC-assays for the measurement of urinary collagen cross-links. J. Endocrinol. Invest. 17, 625-629 (1994). [Pg.288]

G8. Gertz, B. J., Clemens, J. D., Holland, S. D., Yuan, W., and Greenspan, S., Application of a new serum assay for type I collagen cross-linked A-telopeptides Assessment of diurnal changes in bone turnover with and without alendronate treatment. Calcif. Tissue Int. 63,102—106... [Pg.289]

H3. Hanson, D. A., Weis, M. A. E., Bollen, A. M., Maslan, S. L., Singer, F. R., and Eyre, D. R., A specific immunoassay for monitoring human bone resorption Quantitation of type I collagen cross-linked A-telopeptides in urine. J. Bone Miner. Res. 7,1251—1258 (1992). [Pg.290]

R4. Robins, S. P., Collagen cross-links in metabolic bone disease. Acta Orthoped. Scand. 66,171-175 (1995). [Pg.292]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...