Collaborative Approaches to Lead Generation

Fabrizio Ciordanetto, Anna Karawajczyk, and Graham Showell 

Lead Generation Methods, Strate es, and Case Studies, First Edition. Edited by Jorg Holenz. 

---

Lead generation is a key component of successful drug discovery. It is also the phase where the risks associated with drug discovery research are highest A number of collaborative approaches to lead generation have emerged in recent years. These are summarized in Table 11.1 and are reviewed in the following sections. 

As a consequence, relevant results can be evaluated prospectively in future clinical trials. Clearly, the success of such potential cooperative ventures depends on the quality of interaction among the leading institutional and collaborative study groups. Moreover, it is necessary to arrive at a consensus for generating tools needed to develop a more detailed uniform approach for an improved assessment of thiopurine treatment in childhood ALL. 

---