Diabetic ketoacidosis clozapine

Colli A, Cocciolo M, Francobandiera R, et al. Diabetic ketoacidosis associated with clozapine treatment. Diabetes Care 1999 22 176-177. 

Reviews A review of 16 studies evaluated the incidence of four clozapine-related side effects [98 ]. The incidence of agranulocytosis was between 3.8% and 8.0% (mortality rate was 0.1-0.3%) and case fatality rate was 2.2-. 2%. The incidence of diabetic ketoacidosis was 1.2-3.1% and case fatalify rafe was 20-31%. The incidence of gastrointestitml hypomotility was 4-8% and case fatality rate was 15-27.5%. The incidence of myocarditis was 0.07-0.6% (overall) and 7-34% (Australia). 

Endocrine A case of diabetic ketoacidosis occxuring 4 weeks after clozapine initiation is reported in a 29-year-old male [120 ]. 

Kasmi Y. A case of clozapine-induced diabetic ketoacidosis. Psychiatr Bull 2013 37 36. 

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