Clostridium thermoaceticum, acetate synthesis

In contrast, dissimilation of acetate may take place by reversal of the pathway used by organisms snch as Clostridium thermoaceticum for the synthesis of acetate from COj. In the degradation of acetate, the pathway involves a dismutation in which the methyl group is successively oxidized via methyl THF to COj while the carbonyl group is oxidized via bound carbon monoxide. Snch THF-mediated reactions are of great importance in the anaerobic degradation of pnrines, which is discussed in Chapter 10, Part 1. 

Andreesen JR, Schaupp A, Neurauter C, et al. 1973. Fermentation of glucose, fructose, and xylose by Clostridium thermoaceticum effect of metals on growth yield, enzymes, and synthesis of acetate from CO2. J Bacteriol 114 743-51. 

Schulman, M., Ghambeer, R. K., Ljungdahl, L. G., and Wood, H. G., 1973, Total synthesis of acetate from C02. VII. Evidence with Clostridium thermoaceticum that die carboxyl of acetate is derived from the carboxyl of pyruvate by transcarboxylation and not by fixation of CO2, J. Biol. Chem. 248 6255n626L... 

Houchis JP, Hind G (1983) Flash spectroscopic characterization of photosynthetic electron transport in isolated heterocysts. Arch Biochem Biophys 224 272-282 Hu S-I, Pezacka E, Wood HG (1984) Acetate synthesis from carbon monoxide by Clostridium thermoaceticum. Purification of corrinoid protein. J Biol Chem 259 8892-8897 Huber R, Kristjansson JK, Stetter KO (1987) Pyrobaculum gen. nov., a new genus of neutrophilic, rod-shaped archaebacteria from continental solfataras growing optimally at 100°C. Arch Microbiol 149 95-101... 

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