Clarke’s method

By addition of slaked lime, in calculated quantity for the par ticular degree of hardness (Clark s method) ... 

Assigning equal weight to the values of Berzelius and of Maumene, the weighted mean computed by Clarke s method of the preceding results is... 

Clark s Methods in Microscopy. Detailed descriptions of successful methods. 1.60. Coit s Chemical Arithmetic. With a short system of analysis. 50 cents. Coleman s Elements of Physics. For secondary schools. 1.25. 

Clarke s method was worked out for small amounts of antimony in tin but the method is equally applicable to its determination in other substances. 

The silver chlorine ratio was determined by E. Turner (1829),4 F. Penny (1839), J. C. G. de Marignac (1842), J. B. A. Dumas (1860), J. S. Stas (1865), and by T. W. Richards and R. C. Wells (1905) by the precipitation of silver chloride. L. Maumene reduced silver chloride to the metal by heating it in a stream of hydrogen and J. S. Stas also synthesized silver chloride by heating the metal in chlorine gas. This ratio has also been determined by several less direct methods. F. W. Clarke s calculations furnished 32 8606 0 00031 for the general mean representing the amount of chlorine which combines with 100 parts of silver to form silver chloride. 

Clark, S. I. Quantitative Methods of Organic Microanalysis. London Butter-worths 1954. 

Ashby, J., Clark, S. and Craig, RJ. (1988) Methods for the production of volatile organometallic derivatives for application to the analysis of environmental samples. J. Anal. At. Spectrom., 3, 735-736. 

Clarke S. M. Hinchsliffe, K. Jones, H. Wolfe, M.S. Thomas, J. Gibbon, D. Harris, F. and F. Lyon (2006) A participatory approach to variety and mixture trials Methods, results and farmer opinions.- In Cstergard H and L. Fontaine (eds) (2006) Proceedings of the COST SUSVAR workshop on cereal crop diversity Implications for production and products.- ITAB Press, Paris, France. Pp 12-16. 

E.G.C Clark s Isolation and Identification of Drugs (The Pharmaceutical Press, London) specifies a method for making "microtests of a "pedant drop or "microdrop. The sulfuric acid-formaldehyde testing of DMT, to illustrate, yields dull orange with a sensitivity of 1.0 meg. sensitivity, while the ammonium molybdate test yields blue going to green and then yellow with a sensitivity of 0.1 meg. 

Several examples of analysis of actual data by this method are given in Clarke s 17) paper, and we shall discuss below its application to Szilard-Chalmers annealing data. 

Clark and Heathcock59 have reported a recent modification of Conia s method and have found their zinc-silver couple to be very useful for the reduction of /3-chloro-a, 3-unsaturated ketones to a, /3-unsaturated ketones. 

Displacement of ammonium moieties is of huge interest for the rapid synthesis, under very mild conditions, of F-labelled radio-pharmaceuticals useful for medical imaging. Following Clark s work and some others in the 80 s (refs. 2,3) increasing interest is paid to fluorodenitration but this method is limited by the availability of 1,2 or 1,4 dinitrobenzenes. Thus, on an industrial scale, exchange of F for Cl is much preferred (ref. 5). 

Chem. 12, 228 (1920) U.S, pat. 1,318,633 (1920 to Barrett Co.). Many other syntheses. Review of commercial methods of manufacture Ashcroft, Clifford, Chem. Prods. 24, 11 (1961), C.A. 55, 9724d (1961) Faith, Reyes Clark s Industrial Chemicals. F. A. Lower heim, M K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 514-518, Review,- W. D. Robinson, R. A. Mount in Kirk-Othmer Encyclopedia of Chemical Technology vol, 14 (Wiley-Inter-science, New York, 3rd ed., 1981) pp 770-793. Book B. C. Trivedi. B. M. Culbertson, Maleic Anhydride (Plenum, New York, 1982) 872 pp. 

Dr Clark, in Journ. Hoc. Chem. Ind., 1896, recommends for antimony ores and alloys a modification of Mohr s method t of titration with solution of iodine —... 

Early work on the quantum mechanical analysis of chemisorption and chemisorbed states is admirably covered in Clark s monograph. Application of the extended Hiickel molecular orbital method in the hands of A. B. 

Stucki (1978) mainly deals with the stability of the steady states of kinetic differential equations. He gives an introduction to stability theory that is more detailed than those found in the usual textbooks on ordinary differential equations. He also shows how to apply the different methods to problems of biochemical kinetics. His paper also includes some of Clarke s results up to that time. 

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