Citric acid, in urine

Citric Acid. Thunberg (T21) has summarized the steps which led to the identification of citric acid in urine. Found in lemon juice by Scheele in 1784, citric acid was considered a typical plant acid until its presence was shown in milk in 1888. Classified among the normal metabolites by Thunberg since 1910, this acid was found first in animal urine after administration of citrate, then in normal human urine by Amberg and McClure (A6). Later on, it was found also in normal human plasma by Benni et al. (B9). 

Zecin J, Walisch S, Kaczmarowicz G (1978) Spectrophotometiic method of determination of citric acid in fermentation fluids. Przem Ferment i Owocowo-Waizywny 22 20-22 Rajagopal G (1984) A simple colorimetric procedure for estimation of citric acid in urine. Indian Exp Biol 22 391-392... 

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