Citicoline CDP-Choline and TBI

Citicoline (CDP-choline) is an intermediate in PtdCho biosynthesis. It has been used for the treatment of ischemic and head injuries (Andersen et al., 1999 Dempsey and Rao, 2003). It not only restores the concentration of PtdCho following ischemic injury by increasing PtdCho synthesis from diacylglycerol but also blocks the activation of CPLA2 activity (Adibhatla et al., 2002 Adibhatla and Hatcher, 2003). The 

7 Potential Neuroprotective Strategies for Traumatic Brain Injury 

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