Circular dichroism technique

Feasibility of the Induced Circular Dichroism Technique for Nucleic Acid Research... 

Appendix Magnetic Circular Dichroism Techniques Coupled with the Circular Dichroism Technique... 

The chiroptical properties of 2-hydroxyalkanoic acids have been discussed in relation to their stereochemical features in solution. The potential of circular dichroism techniques was emphasized... 

During the past decade there has been a considerable resurgence of interest in the optical rotatory dispersion and circular dichroism of coordination compounds. In addition, there also has been a considerable renewal of interest in the Pfeiffer effect during this same period of time. This coincidental renewal of interest in these fields is most fortunate, because it is possible to apply optical rotatory dispersion and circular dichroism techniques to the study of the Pfeiffer effect with fruitful results vide infra). 

The Danielli-Davson model has been modified by Wallach and Zahler (1966) who demonstrated by optical rotatory dispersion and circular dichroism techniques that a substantial amount of membrane protein exists in a helical conformation as opposed to random coil It is envisioned that hydrophilic portions of membrane protein are located on both sides of the membrane and are connected by hydrophobic microtubules. Lenard and Singer (1966) also advanced similar views and suggested that subunits could result from this model which, when assembled in two dimensions, could form a membrane. 

Let us now consider the results obtained by investigating the polymeric complexes with circular dichroism techniques. Before going into details it is worth mentioning that it is not possible to study in solution polymers with more than — 20% of the side chains com-plexed, as they precipitate when the degree of formation exceeds this value. 

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