Cinnoline synthesis

An important early method simulated the well-known Widman-Stoermer cinnoline synthesis. 3-Aminopyridine-2- or -4-alkenes such as (348) gave pyrido-[3,2-c]- or -[3,4-c]-pyridazines on diazotization and alkaline cyclization (66JCS(C)2053>. 

The only example of a simple pyridopyridazine synthesis of this kind from a pyridine intermediate involves a variant of a well known cinnoline synthesis in which the Japp-Klingemann intermediate (363) gives the pyrido[3,4-c]pyridazine (364) with PPA (69JHC977). 

Barrellene oxide flash thermolysis oxirenes in, 7, 125 Basic Violet 10 (C.I. 45170), 3, 879 Batrachotoxin, 4, 374 Baumgarten method cinnoline synthesis, 3, 44... 

Pyrido[2,3-c]cinnolines synthesis, 3, 242, 245 Pyrido[3,2-c]cinnolines synthesis, 3, 242, 245 Pyrido[3,4-c]cinnolines synthesis, 3, 242, 244, 245 Pyrido[4,3-c]cinnolines synthesis, 3, 242, 245 Py rido[ 18]crown-6 t-butylammonium complex... 

Pyrrolo[2,1 -c][l, 4]benzodiazepines synthesis, 7, 614 Pyrrolo[l, 6]benzodiazocines synthesis, 7, 515 Pyrrolo[3,4-c]benzopyrazoles reactions, 6, 1034 Pyrrolobenzothiazoles synthesis, 4, 785 Pyrrolo[l, 2-c]benzotriazines synthesis, 4, 240 Pyrrolo[3,4-c]cinnolines synthesis, 4, 240... 

RICHTER - WIDMAN STOERMER Cinnoline Synthesis Synthesis of cinnolines from substituted anilines via diazonium salts. 

The thermal cyclization of 2-alkynylbenzenediazonium salts represented by 2 to provide the 4-hydroxycinnoline derivatives 3 respectively is regarded as the von Richter cinnoline synthesis. " ... 

The mechanism of the von Richter cinnoline synthesis has been discussed in several... 

Borsche cinnoline synthesis 141 Bromo-de-diazoniation 194, 230ff., 270, 301... 

See the Borsche Cinnoline Synthesis and the von Richter Cinnoline Synthesis for other preparations of cinnolines. 

Bart Reaction Borsche (Cinnoline) Synthesis Demianov Rearranement Diazo Reaction Gattermann Reaction Gattermann Method Pschorr Arvlation Sandmever Reaction Schiemann Reaction (Bak-Schiemann JRxn) Tiffeneau-Demianov Reaction fVidman-Stoermer ([Pg.847]

Cyclopent-2-en-l-one, 2-hydroxy-3-methyl-synthesis, 3, 693 Cyclopentenone, 4-methoxy-formation, 1, 423 Cyclopenthiazide as diuretic, 1, 174 Cyclopent[2,3-d]isoxazol-4-one structure, 6, 975 Cydophane conformation, 2, 115 photoelectron spectroscopy, 2, 140 [2,2]Cydophane conformation, 2, 115 Cyclophanes nomenclature, 1, 27 Cyclophosphamide as pharmaceutical, 1, 157 reviews, 1, 496 Cydopiloselloidin synthesis, 3, 743 Cydopolymerization heterocycle-forming, 1, 292-293 6 ff-Cy clopropa[5 a,6a]pyrazolo[ 1,5- a]pyrimidine pyrazoles from, S, 285 Cy dopropab enzopy ran synthesis, 3, 700 Cydopropachromenes synthesis, 3, 671 Cyclopropa[c]cinnolines synthesis, 7, 597 Cyclopropanation by carbenes... 

NEBER-BOSSET Oxindole Cinnoline Synthesis Synthesis of N-aminooxindoles or of cinnolines (see 1st edition). 

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